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Linked spontaneous CG----TA mutations at CpG sites in the gene for protein kinase regulatory subunit.
CG----TA transitions at CpG sequences account for many human point mutations and are thought to result from hydrolytic deamination of 5-methylcytosine residues in these sites. The gene for regulatory subunit of murine cyclic AMP-dependent protein kinase has two closely linked CpG sites, one of which...
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| Publicado en: | Mol Cell Biol |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Taylor & Francis
1992
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364294/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1310152/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.2.767 |
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