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Accurate Quantitation of Dystrophin Protein in Human Skeletal Muscle Using Mass Spectrometry

Quantitation of human dystrophin protein in muscle biopsies is a clinically relevant endpoint for both diagnosis and response to dystrophin-replacement therapies for dystrophinopathies. A robust and accurate assay would enable the use of dystrophin as a surrogate biomarker, particularly in explorato...

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מידע ביבליוגרפי
Main Authors: Brown, Kristy J., Marathi, Ramya, Fiorillo, Alyson A., Ciccimaro, Eugene F., Sharma, Seema, Rowlands, David S., Rayavarapu, Sree, Nagaraju, Kanneboyina, Hoffman, Eric P., Hathout, Yetrib
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642779/
https://ncbi.nlm.nih.gov/pubmed/23646235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/1948-593X.S7-001
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