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Accurate Quantitation of Dystrophin Protein in Human Skeletal Muscle Using Mass Spectrometry
Quantitation of human dystrophin protein in muscle biopsies is a clinically relevant endpoint for both diagnosis and response to dystrophin-replacement therapies for dystrophinopathies. A robust and accurate assay would enable the use of dystrophin as a surrogate biomarker, particularly in explorato...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3642779/ https://ncbi.nlm.nih.gov/pubmed/23646235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/1948-593X.S7-001 |
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