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Another fork in the road—life or death decisions by the tumour suppressor p53
In response to cellular stress signals, the tumour suppressor p53 accumulates and triggers a host of antineoplastic responses. For instance, DNA damage activates two main p53-dependent responses: cell cycle arrest and attendant DNA repair or apoptosis (cell death). It is broadly accepted that, in re...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
European Molecular Biology Organization
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3642373/ https://ncbi.nlm.nih.gov/pubmed/23588418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2013.25 |
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