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Life-and-Death Decision-Making by p53 and Implications in Cancer Immunotherapy
The tumor suppressor p53 is mutated in approximately half of all cancers, whereas the p53 signaling network is perturbed in almost all cancers. In response to different stress stimuli, p53 selectively activates genes to elicit a cell survival or cell death response. How p53 makes the decision betwee...
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| Publicado no: | Trends Cancer |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7889652/ https://ncbi.nlm.nih.gov/pubmed/33199193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2020.10.005 |
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