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Life-and-Death Decision-Making by p53 and Implications in Cancer Immunotherapy

The tumor suppressor p53 is mutated in approximately half of all cancers, whereas the p53 signaling network is perturbed in almost all cancers. In response to different stress stimuli, p53 selectively activates genes to elicit a cell survival or cell death response. How p53 makes the decision betwee...

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Foilsithe in:Trends Cancer
Main Authors: Liu, Yong, Leslie, Patrick L., Zhang, Yanping
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7889652/
https://ncbi.nlm.nih.gov/pubmed/33199193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2020.10.005
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