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Another fork in the road—life or death decisions by the tumour suppressor p53

In response to cellular stress signals, the tumour suppressor p53 accumulates and triggers a host of antineoplastic responses. For instance, DNA damage activates two main p53-dependent responses: cell cycle arrest and attendant DNA repair or apoptosis (cell death). It is broadly accepted that, in re...

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Detalhes bibliográficos
Main Authors: Carvajal, Luis A, Manfredi, James J
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642373/
https://ncbi.nlm.nih.gov/pubmed/23588418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2013.25
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