Cell-type-specific expression of the rat thyroperoxidase promoter indicates common mechanisms for thyroid-specific gene expression.

A 420-bp fragment from the 5' end of the rat thyroperoxidase (TPO) gene was fused to a luciferase reporter and shown to direct cell-type-specific expression when transfected into rat thyroid FRTL-5 cells. Analysis of this DNA fragment revealed four regions of the promoter which interact with DNA-bin...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Francis-Lang, H, Price, M, Polycarpou-Schwarz, M, Di Lauro, R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364231/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1732732/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.2.576-588.1992
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