Substrate Specificity of MarP, a Periplasmic Protease Required for Resistance to Acid and Oxidative Stress in Mycobacterium tuberculosis

The transmembrane serine protease MarP is important for pH homeostasis in Mycobacterium tuberculosis (Mtb). Previous structural studies revealed that MarP contains a chymotrypsin fold and a disulfide bond that stabilizes the protease active site in the substrate-bound conformation. Here, we determin...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Small, Jennifer L., O'Donoghue, Anthony J., Boritsch, Eva C., Tsodikov, Oleg V., Knudsen, Giselle M., Vandal, Omar, Craik, Charles S., Ehrt, Sabine
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2013
Gaiak:
Enzymology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3642297/
https://ncbi.nlm.nih.gov/pubmed/23504313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.456541
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