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Structural insight into serine protease Rv3671c that protects M. tuberculosis from oxidative and acidic stress

Rv3671c, a putative serine protease, is crucial for persistence of M. tuberculosis in the hostile environment of the phagosome. We show that Rv3671c is required for M. tuberculosis resistance to oxidative stress in addition to its role in protection from acidification. Structural and biochemical ana...

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Detalhes bibliográficos
Main Authors: Biswas, Tapan, Small, Jennifer, Vandal, Omar, Odaira, Toshiko, Deng, Haiteng, Ehrt, Sabine, Tsodikov, Oleg V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955984/
https://ncbi.nlm.nih.gov/pubmed/20947023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.06.017
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