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Mitochondrial Complex I Function Modulates Volatile Anesthetic Sensitivity in C. elegans

Despite the widespread clinical use of volatile anesthetics, their mechanisms of action remain unknown [1–6]. An unbiased genetic screen in the nematode C. elegans for animals with altered volatile anesthetic sensitivity identified a mutant in a nuclear-encoded subunit of mitochondrial complex I [7,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Falk, Marni J., Kayser, Ernst-Bernhard, Morgan, Philip G., Sedensky, Margaret M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641903/
https://ncbi.nlm.nih.gov/pubmed/16920626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2006.06.072
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