Genetically engineered mouse models for functional studies of SKP1-CUL1-F-box-protein (SCF) E3 ubiquitin ligases

The SCF (SKP1 (S-phase-kinase-associated protein 1), Cullin-1, F-box protein) E3 ubiquitin ligases, the founding member of Cullin-RING ligases (CRLs), are the largest family of E3 ubiquitin ligases in mammals. Each individual SCF E3 ligase consists of one adaptor protein SKP1, one scaffold protein c...

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Main Authors: Zhou, Weihua, Wei, Wenyi, Sun, Yi
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2013
Assuntos:
Review
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641602/
https://ncbi.nlm.nih.gov/pubmed/23528706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.44
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