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ISG15: leading a double life as a secreted molecule

ISG15 is a well-known intracellular ubiquitin-like molecule involved in ISGylation. However, a recent study has revived the notion first put forward two decades ago that ISG15 is also a secreted molecule. Human neutrophils, monocytes and lymphocytes can release ISG15, even though this protein has no...

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Bibliografiske detaljer
Main Authors: Bogunovic, Dusan, Boisson-Dupuis, Stéphanie, Casanova, Jean-Laurent
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641400/
https://ncbi.nlm.nih.gov/pubmed/23579383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2013.36
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