Expression, regulation and clinical relevance of the ATPase inhibitory factor 1 in human cancers

Recent findings in colon cancer cells indicate that inhibition of the mitochondrial H(+)-adenosine triphosphate (ATP) synthase by the ATPase inhibitory factor 1 (IF1) promotes aerobic glycolysis and a reactive oxygen species (ROS)-mediated signal that enhances proliferation and cell survival. Herein...

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Autori principali: Sánchez-Aragó, M, Formentini, L, Martínez-Reyes, I, García-Bermudez, J, Santacatterina, F, Sánchez-Cenizo, L, Willers, I M, Aldea, M, Nájera, L, Juarránz, Á, López, E C, Clofent, J, Navarro, C, Espinosa, E, Cuezva, J M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641363/
https://ncbi.nlm.nih.gov/pubmed/23608753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2013.9
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