Degradation of IF1 controls energy metabolism during osteogenic differentiation of stem cells

Differentiation of human mesenchymal stem cells (hMSCs) requires the rewiring of energy metabolism. Herein, we demonstrate that the ATPase inhibitory factor 1 (IF1) is expressed in hMSCs and in prostate and colon stem cells but is not expressed in the differentiated cells. IF1 inhibits oxidative pho...

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Detalhes bibliográficos
Main Authors: Sánchez-Aragó, María, García-Bermúdez, Javier, Martínez-Reyes, Inmaculada, Santacatterina, Fulvio, Cuezva, José M
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701239/
https://ncbi.nlm.nih.gov/pubmed/23722655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2013.72
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