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Imbalance of p75(NTR)/TrkB protein expression in Huntington's disease: implication for neuroprotective therapies
Neuroprotective therapies based on brain-derived neurotrophic factor (BDNF) administration have been proposed for Huntington's disease (HD) treatment. However, our group has recently reported reduced levels of TrkB in HD mouse models and HD human brain suggesting that besides a decrease on BDNF...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3641339/ https://ncbi.nlm.nih.gov/pubmed/23598407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.116 |
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