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Transcription Factors That Convert Adult Cell Identity Are Differentially Polycomb Repressed

Transcription factors that can convert adult cells of one type to another are usually discovered empirically by testing factors with a known developmental role in the target cell. Here we show that standard genomic methods (RNA-seq and ChIP-seq) can help identify these factors, as most are more stro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Davis, Fred P., Eddy, Sean R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641127/
https://ncbi.nlm.nih.gov/pubmed/23650565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063407
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