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Transcription Factors That Convert Adult Cell Identity Are Differentially Polycomb Repressed

Transcription factors that can convert adult cells of one type to another are usually discovered empirically by testing factors with a known developmental role in the target cell. Here we show that standard genomic methods (RNA-seq and ChIP-seq) can help identify these factors, as most are more stro...

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Detalhes bibliográficos
Main Authors: Davis, Fred P., Eddy, Sean R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641127/
https://ncbi.nlm.nih.gov/pubmed/23650565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063407
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