Kif3a Guides Microtubular Dynamics, Migration and Lumen Formation of MDCK Cells

The microtubular motor Kinesin-2 and its subunit Kif3a are essential for the formation of primary cilia, an organelle implicated in a wide spectrum of developmental abnormalities. Outside cilia, Kinesin-2 mediated transport has been implicated in vesicle and N-cadherin transport, but it is unknown i...

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Bibliographic Details
Main Authors: Boehlke, Christopher, Kotsis, Fruzsina, Buchholz, Bjoern, Powelske, Christian, Eckardt, Kai-Uwe, Walz, Gerd, Nitschke, Roland, Kuehn, E. Wolfgang
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641035/
https://ncbi.nlm.nih.gov/pubmed/23658710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062165
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