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Design, Mechanism of Action, Bioavailability and Therapeutic Effects of Mn Porphyrin-Based Redox Modulators

Based on aqueous redox chemistry and simple in vivo models of oxidative stress, Escherichia coli and Saccharomyces cerevisiae, the cationic Mn(III) N-substituted pyridylporphyrins (MnPs) have been identified as the most potent cellular redox modulators within the porphyrin class of drugs; their effi...

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Autors principals: Tovmasyan, Artak, Sheng, Huaxin, Weitner, Tin, Arulpragasam, Amanda, Lu, Miaomiao, Warner, David S., Vujaskovic, Zeljko, Spasojevic, Ivan, Batinic-Haberle, Ines
Format: Artigo
Idioma:Inglês
Publicat: S. Karger AG 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640855/
https://ncbi.nlm.nih.gov/pubmed/23075911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000341715
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