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Transgenes expressing the Wnt-1 and int-2 proto-oncogenes cooperate during mammary carcinogenesis in doubly transgenic mice.

The Wnt-1 and int-2 proto-oncogenes are transcriptionally activated by mouse mammary tumor virus insertion mutations in virus-induced tumors and encode secretory glycoproteins. To determine whether these two genes can cooperate during carcinogenesis, we have crossed two previously characterized line...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Kwan, H, Pecenka, V, Tsukamoto, A, Parslow, T G, Guzman, R, Lin, T P, Muller, W J, Lee, F S, Leder, P, Varmus, H E
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1992
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Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364078/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1530875/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.12.1.147
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