Transgenes expressing the Wnt-1 and int-2 proto-oncogenes cooperate during mammary carcinogenesis in doubly transgenic mice.

The Wnt-1 and int-2 proto-oncogenes are transcriptionally activated by mouse mammary tumor virus insertion mutations in virus-induced tumors and encode secretory glycoproteins. To determine whether these two genes can cooperate during carcinogenesis, we have crossed two previously characterized line...

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Hauptverfasser: Kwan, H, Pecenka, V, Tsukamoto, A, Parslow, T G, Guzman, R, Lin, T P, Muller, W J, Lee, F S, Leder, P, Varmus, H E
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1992
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC364078/
https://ncbi.nlm.nih.gov/pubmed/1530875
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