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The mouse homolog of the hst/k-FGF gene is adjacent to int-2 and is activated by proviral insertion in some virally induced mammary tumors.

The fibroblast growth factor-related protooncogenes, int-2 and hst/k-FGF, are within 17 kilobase pairs of one another on mouse chromosome 7 and are in the same transcriptional orientation. Approximately 70% of tumors induced in BR6 mice by mouse mammary tumor virus have proviral insertions adjacent...

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Bibliographic Details
Main Authors: Peters, G, Brookes, S, Smith, R, Placzek, M, Dickson, C
Format: Artigo
Language:Inglês
Published: 1989
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC297693/
https://ncbi.nlm.nih.gov/pubmed/2548184
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