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Opioids and clonidine modulate cytokine production and opioid receptor expression in neonatal immune cells

OBJECTIVE: Opioids and clonidine, used in for sedation, analgesia and control of opioid withdrawal in neonates, directly or indirectly activate opioid receptors expressed in immune cells. Therefore, our objective is to study how clinically relevant concentrations of different opioids and clonidine c...

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Detalhes bibliográficos
Main Authors: Chavez-Valdez, Raul, Kovell, Lara, Ahlawat, Rajni, McLemore, Gabrielle L., Wills-Karp, Marsha, Gauda, Estelle B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640758/
https://ncbi.nlm.nih.gov/pubmed/23047422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jp.2012.124
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