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An Image-Based Biosensor Assay Strategy to Screen for Modulators of the microRNA 21 Biogenesis Pathway

microRNAs (miRNAs) are evolutionary conserved, small endogenous non-coding, RNA molecules. Although their mode of action has been extensively studied, little is known about their biogenesis. As their altered expression has been implicated in many diseases, small molecules that would modulate their e...

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Auteurs principaux: Shum, David, Bhinder, Bhavneet, Radu, Constantin, Calder, Paul, Ramirez, Christina N., Djaballah, Hakim
Format: Artigo
Langue:Inglês
Publié: 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640486/
https://ncbi.nlm.nih.gov/pubmed/22540737
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