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Age and CYP3A5 genotype affect tacrolimus dosing requirements after transplant in pediatric heart recipients
BACKGROUND: Tacrolimus is one of the commonly used immunosuppressive drugs for pediatric heart transplants. Large variation exists in pharmacokinetics during the direct post-transplant period, resulting in an increased risk of adverse events. Limited data are available on the interaction of age, CYP...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3640375/ https://ncbi.nlm.nih.gov/pubmed/21930396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.healun.2011.08.001 |
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