The interactions of age, genetics, and disease severity on tacrolimus dosing requirements after pediatric kidney and liver transplantation

PURPOSE: In children, data on the combined impact of age, genotype, and disease severity on tacrolimus (TAC) disposition are scarce. The aim of this study was to evaluate the effect of these covariates on tacrolimus dose requirements in the immediate post-transplant period in pediatric kidney and li...

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Hlavní autoři: de Wildt, Saskia N., van Schaik, Ron H. N., Soldin, Offie P., Soldin, Steve J., Brojeni, Parvaneh Yazdani, van der Heiden, Ilse P., Parshuram, Chris, Nulman, Irena, Koren, Gideon
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2011
Témata:
Pharmacogenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214266/
https://ncbi.nlm.nih.gov/pubmed/21698374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-011-1083-7
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