Hyperinsulinemia does not change atherosclerosis development in apolipoprotein E null mice

OBJECTIVE: To determine the contribution of hyperinsulinemia to atherosclerosis development. METHODS AND RESULTS: Apolipoprotein E (Apoe) null mice which had knockout of one allele of the insulin receptor (Insr) gene were compared with littermate Apoe null mice with intact insulin receptors. Plasma...

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Hauptverfasser: Rask-Madsen, Christian, Buonomo, Erica, Li, Qian, Park, Kyoungmin, Clermont, Allen C., Yerokun, Oluwatobi, Rekhter, Mark, King, George L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640325/
https://ncbi.nlm.nih.gov/pubmed/22426129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.239558
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