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Modeling Clear Cell Sarcomagenesis in the Mouse: cell of origin differentiation state impacts tumor characteristics

Clear cell sarcoma (CCS) of tendons and aponeuroses is a deadly soft-tissue malignancy resembling melanoma, with a predilection for young adults. EWS-ATF1, the fusion product of a balanced chromosomal translocation between chromosomes 22 and 12, is considered the definitional feature of the tumor. C...

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Detalhes bibliográficos
Main Authors: Straessler, Krystal M., Jones, Kevin B., Hu, Hao, Jin, Huifeng, van de Rijn, Matt, Capecchi, Mario R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640275/
https://ncbi.nlm.nih.gov/pubmed/23410975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2012.12.019
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