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Phenotyping the Function of TRPV1-Expressing Sensory Neurons by Targeted Axonal Silencing

Specific somatosensations may be processed by different subsets of primary afferents. C-fibers expressing heat-sensitive TRPV1 channels are proposed, for example, to be heat but not mechanical pain detectors. To phenotype in rats the sensory function of TRPV1(+) afferents, we rapidly and selectively...

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Auteurs principaux: Brenneis, Christian, Kistner, Katrin, Puopolo, Michelino, Segal, David, Roberson, David, Sisignano, Marco, Labocha, Sandra, Ferreirós, Nerea, Strominger, Amanda, Cobos, Enrique J., Ghasemlou, Nader, Geisslinger, Gerd, Reeh, Peter W., Bean, Bruce P., Woolf, Clifford J.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2013
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640269/
https://ncbi.nlm.nih.gov/pubmed/23283344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2804-12.2013
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