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Discovery Of Peptoid Ligands For Anti-Aquaporin 4 Antibodies

Neuromyelitis optica (NMO) is an autoimmune inflammatory disorder of the central nervous system. In most NMO patients, autoantibodies to the water channel protein Aquaporin 4 (AQP4) are present at high levels and are thought to drive pathology by mediating complement-dependent destruction of astrocy...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Raveendra, Bindu, Hao, Wu, Baccala, Roberto, Reddy, M. Muralidhar, Schilke, Jessica, Bennett, Jeffrey L., Theofilopoulos, Argyrios N., Kodadek, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640264/
https://ncbi.nlm.nih.gov/pubmed/23521793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2012.12.009
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