Short- and Long-Term Effects of LRRK2 on Axon and Dendrite Growth

Mutations in leucine-rich repeat kinase 2 (LRRK2) underlie an autosomal-dominant form of Parkinson's disease (PD) that is clinically indistinguishable from idiopathic PD. The function of LRRK2 is not well understood, but it has become widely accepted that LRRK2 levels or its kinase activity, wh...

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Autors principals: Sepulveda, Bryan, Mesias, Roxana, Li, Xianting, Yue, Zhenyu, Benson, Deanna L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640004/
https://ncbi.nlm.nih.gov/pubmed/23646112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061986
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