MERTK receptor tyrosine kinase is a therapeutic target in melanoma

Metastatic melanoma is one of the most aggressive forms of cutaneous cancers. Although recent therapeutic advances have prolonged patient survival, the prognosis remains dismal. C-MER proto-oncogene tyrosine kinase (MERTK) is a receptor tyrosine kinase with oncogenic properties that is often overexp...

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Detalhes bibliográficos
Main Authors: Schlegel, Jennifer, Sambade, Maria J., Sather, Susan, Moschos, Stergios J., Tan, Aik-Choon, Winges, Amanda, DeRyckere, Deborah, Carson, Craig C., Trembath, Dimitri G., Tentler, John J., Eckhardt, S. Gail, Kuan, Pei-Fen, Hamilton, Ronald L., Duncan, Lyn M., Miller, C. Ryan, Nikolaishvili-Feinberg, Nana, Midkiff, Bentley R., Liu, Jing, Zhang, Weihe, Yang, Chao, Wang, Xiaodong, Frye, Stephen V., Earp, H. Shelton, Shields, Janiel M., Graham, Douglas K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3639697/
https://ncbi.nlm.nih.gov/pubmed/23585477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67816
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