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A tumor suppressor role of the Bub3 spindle checkpoint protein after apoptosis inhibition
Most solid tumors contain aneuploid cells, indicating that the mitotic checkpoint is permissive to the proliferation of chromosomally aberrant cells. However, mutated or altered expression of mitotic checkpoint genes accounts for a minor proportion of human tumors. We describe a Drosophila melanogas...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3639401/ https://ncbi.nlm.nih.gov/pubmed/23609535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201210018 |
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