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Determination of ATP and ADP Secretion from Human and Mouse Platelets by an HPLC Assay

SUMMARY: BACKGROUND: Secretion of ADP and ATP is an essential prerequisite for platelet aggregation. Impaired nucleotide secretion can cause aggregation defects and increased bleeding risk. Quantitative determination of platelet nucleotide content and exocytosis is thus of importance for the charact...

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Bibliografiske detaljer
Main Authors: von Papen, Michael, Gambaryan, Stepan, Schütz, Claudia, Geiger, Jörg
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger GmbH 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638993/
https://ncbi.nlm.nih.gov/pubmed/23652982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000350294
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