ADP is not an agonist at P2X(1) receptors: evidence for separate receptors stimulated by ATP and ADP on human platelets

1. ADP, an important agonist in thrombosis and haemostasis, has been reported to activate platelets via three receptors, P2X(1), P2Y(1) and P2T(AC). Given the low potency of ADP at P2X(1) receptors and recognized contamination of commercial samples of adenosine nucleotides, we have re-examined the a...

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Bibliographic Details
Main Authors: Mahaut-Smith, Martyn P, Ennion, Steven J, Rolf, Michael G, Evans, Richard J
Format: Artigo
Language:Inglês
Published: 2000
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Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572284/
https://ncbi.nlm.nih.gov/pubmed/10960076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703517
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