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ADP is not an agonist at P2X(1) receptors: evidence for separate receptors stimulated by ATP and ADP on human platelets

1. ADP, an important agonist in thrombosis and haemostasis, has been reported to activate platelets via three receptors, P2X(1), P2Y(1) and P2T(AC). Given the low potency of ADP at P2X(1) receptors and recognized contamination of commercial samples of adenosine nucleotides, we have re-examined the a...

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Hlavní autoři: Mahaut-Smith, Martyn P, Ennion, Steven J, Rolf, Michael G, Evans, Richard J
Médium: Artigo
Jazyk:Inglês
Vydáno: 2000
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572284/
https://ncbi.nlm.nih.gov/pubmed/10960076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703517
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