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A disease-associated PTPN22 variant promotes systemic autoimmunity in murine models
Multiple autoimmune diseases, including type 1 diabetes, rheumatoid arthritis, Graves disease, and systemic lupus erythematosus, are associated with an allelic variant of protein tyrosine phosphatase nonreceptor 22 (PTPN22), which encodes the protein LYP. To model the human disease-linked variant LY...
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| Autori principali: | , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3638909/ https://ncbi.nlm.nih.gov/pubmed/23619366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66963 |
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