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PLG Scaffold Delivered Antigen-Specific Regulatory T Cells Induce Systemic Tolerance in Autoimmune Diabetes

Islet transplantation is a promising treatment for human type 1 diabetes mellitus. Transplantation requires systemic immunosuppression, which has numerous deleterious side effects. Islet antigen-specific regulatory T cells (Tregs) have been shown to protect islet grafts from autoimmune destruction i...

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Bibliografische gegevens
Hoofdauteurs: Graham, John G., Zhang, Xiaomin, Goodman, Ashley, Pothoven, Kathryn, Houlihan, Josetta, Wang, Shusen, Gower, R. Michael, Luo, Xunrong, Shea, Lonnie D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Mary Ann Liebert, Inc. 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638535/
https://ncbi.nlm.nih.gov/pubmed/23432371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2012.0643
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