Permanent Protection of PLG Scaffold Transplanted Allogeneic Islet Grafts in Diabetic Mice Treated with ECDI-fixed Donor Splenocyte Infusions

Allogeneic islet cell transplantation is a promising treatment for human type 1 diabetes. Currently, human islets are transplanted via intra-portal infusions. While successful, it leads to significant early islet attrition from instant blood-mediated inflammatory reaction. An extra-hepatic site was...

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Detalhes bibliográficos
Main Authors: Kheradmand, Taba, Wang, Shusen, Gibly, Romie F., Zhang, Xiaomin, Holland, Samantha, Tasch, James, Graham, Jack G., Kaufman, Dixon B., Miller, Stephen D., Shea, Lonnie D., Luo, Xunrong
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387923/
https://ncbi.nlm.nih.gov/pubmed/21458857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2011.03.009
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