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Extrahepatic islet transplantation with microporous polymer scaffolds in syngeneic mouse and allogeneic porcine models

Intraportal transplantation of islets has successfully treated select patients with type 1 diabetes. However, intravascular infusion and the intrahepatic site contribute to significant early and late islet loss, yet a clinical alternative has remained elusive. We investigated non-encapsulating, poro...

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Detalhes bibliográficos
Main Authors: Gibly, Romie F., Zhang, Xiaomin, Graham, Melanie L., Hering, Bernhard J., Kaufman, Dixon B., Lowe, William L., Shea, Lonnie D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195897/
https://ncbi.nlm.nih.gov/pubmed/21959005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2011.08.084
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