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Extracellular Matrix Protein-Coated Scaffolds Promote the Reversal of Diabetes After Extrahepatic Islet Transplantation

BACKGROUND: The survival and function of transplanted pancreatic islets is limited, owing in part to disruption of islet-matrix attachments during the isolation procedure. Using polymer scaffolds as a platform for islet transplantation, we investigated the hypothesis that replacement of key extracel...

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Autores principales: Salvay, David M., Rives, Christopher B., Zhang, Xiaomin, Chen, Fei, Kaufman, Dixon B., Lowe, William L., Shea, Lonnie D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597660/
https://ncbi.nlm.nih.gov/pubmed/18497687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e31816fc0ea
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