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Effects of Urotensin II Receptor Antagonist, GSK1440115, in Asthma

Background: Urotensin II (U-II) is highly expressed in the human lung and has been implicated in regulating respiratory physiology in preclinical studies. Our objective was to test antagonism of the urotensin (UT) receptor by GSK1440115, a novel, competitive, and selective inhibitor of the UT recept...

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Detalhes bibliográficos
Main Authors: Portnoy, Alison, Kumar, Sanjay, Behm, David J., Mahar, Kelly M., Noble, Robert B., Throup, John P., Russ, Steven F.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638148/
https://ncbi.nlm.nih.gov/pubmed/23641215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2013.00054
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