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An integrative variant analysis pipeline for accurate genotype/haplotype inference in population NGS data
Next-generation sequencing is a powerful approach for discovering genetic variation. Sensitive variant calling and haplotype inference from population sequencing data remain challenging. We describe methods for high-quality discovery, genotyping, and phasing of SNPs for low-coverage (approximately 5...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3638139/ https://ncbi.nlm.nih.gov/pubmed/23296920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.146084.112 |
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