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Augmentation of Smad-dependent BMP signaling in neural crest cells causes craniosynostosis in mice

Craniosynostosis describes conditions in which one or more sutures of the infant skull are prematurely fused, resulting in facial deformity and delayed brain development. Approximately 20% of human craniosynostoses are thought to result from gene mutations altering growth factor signaling; however,...

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Bibliografske podrobnosti
Main Authors: Komatsu, Yoshihiro, Yu, Paul B., Kamiya, Nobuhiro, Pan, Haichun, Fukuda, Tomokazu, Scott, Gregory J., Ray, Manas K., Yamamura, Ken-ichi, Mishina, Yuji
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638058/
https://ncbi.nlm.nih.gov/pubmed/23281127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.1857
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