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Identification of upregulated phosphoinositide 3-kinase γ as a target to suppress breast cancer cell migration and invasion
Metastasis is the major cause of breast cancer mortality. We recently reported that aberrant G-protein coupled receptor (GPCR) signaling promotes breast cancer metastasis by enhancing cancer cell migration and invasion. Phosphatidylinositol 3-kinase γ (PI3Kγ) is specifically activated by GPCRs. The...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3637857/ https://ncbi.nlm.nih.gov/pubmed/23500535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2013.03.001 |
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