Breast Cancer Migration and Invasion Depend on Proteasome Degradation of Regulator of G-Protein Signaling 4

Aberrant signaling through G-protein coupled receptors promotes metastasis, the major cause of breast cancer death. We identified regulator of G-protein signaling 4 (RGS4) as a novel suppressor of breast cancer migration and invasion, important steps of metastatic cascades. By blocking signals initi...

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Huvudupphovsmän: Xie, Yan, Wolff, Dennis W., Wei, Taotao, Wang, Bo, Deng, Caishu, Kirui, Joseph K., Jiang, Haihong, Qin, Jianbing, Abel, Peter W., Tu, Yaping
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741027/
https://ncbi.nlm.nih.gov/pubmed/19549919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3564
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