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Inefficient TLR4/MD-2 Heterotetramerization by Monophosphoryl Lipid A
Synthetic forms of E. coli monophosphoryl lipid A (sMLA) weakly activate the MyD88 (myeloid differentiation primary response protein) branch of the bifurcated TLR4 (Toll-like receptor 4) signaling pathway, in contrast to diphosphoryl lipid A (sDLA), which is a strong activator of both branches of TL...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3637451/ https://ncbi.nlm.nih.gov/pubmed/23638128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062622 |
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