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Selective Activation of the p38 MAPK Pathway by Synthetic Monophosphoryl Lipid A
TLR4 stimulation by lipopolysaccharide can cause both MAL/MyD88- and TRAM/TRIF (Toll IL-1 receptor domain-containing adaptor-inducing IFNβ)-dependent signaling events. Monophosphoryl lipid A (MPLA), a low toxicity derivative of endotoxic lipopolysaccharide, enhances antibody responses, T cell expans...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2797270/ https://ncbi.nlm.nih.gov/pubmed/19759006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.046383 |
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