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Structural Basis of the Induced-Fit Mechanism of 1,4-Dihydroxy-2-Naphthoyl Coenzyme A Synthase from the Crotonase Fold Superfamily

1, 4-Dihydroxy-2-naphthoyl coenzyme A (DHNA-CoA) synthase is a typical crotonase fold enzyme with an implicated role of conformational changes in catalysis. We have identified these conformational changes by determining the structures of its Escherichia coli and Synechocystis sp. PCC6803 orthologues...

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Main Authors: Sun, Yueru, Song, Haigang, Li, Jie, Li, Yan, Jiang, Ming, Zhou, Jiahai, Guo, Zhihong
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637252/
https://ncbi.nlm.nih.gov/pubmed/23658663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063095
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